Browse Articles

A new therapy against MDR bacteria by in silico virtual screening of Pseudomonas aeruginosa LpxC inhibitors

Liu et al. | Apr 27, 2022

A new therapy against MDR bacteria by <em>in silico</em> virtual screening of <em>Pseudomonas aeruginosa</em> LpxC inhibitors

Here, seeking to address the growing threat of multidrug-resistant bacteria (MDR). the authors used in silico virtual screening to target MDR Pseudomonas aeruginosa. They considered a key protein in its biosynthesis and virtually screened 20,000 candidates and 30 derivatives of brequinar. In the end, they identified a possible candidate with the highest degree of potential to inhibit the pathogen's lipid A synthesis.

Read More...

Population Forecasting by Population Growth Models based on MATLAB Simulation

Li et al. | Aug 31, 2020

Population Forecasting by Population Growth Models based on MATLAB Simulation

In this work, the authors investigate the accuracy with which two different population growth models can predict population growth over time. They apply the Malthusian law or Logistic law to US population from 1951 until 2019. To assess how closely the growth model fits actual population data, a least-squared curve fit was applied and revealed that the Logistic law of population growth resulted in smaller sum of squared residuals. These findings are important for ensuring optimal population growth models are implemented to data as population forecasting affects a country's economic and social structure.

Read More...

The Clinical Accuracy of Non-Invasive Glucose Monitoring for ex vivo Artificial Pancreas

Levy et al. | Jul 10, 2016

The Clinical Accuracy of Non-Invasive Glucose Monitoring for <i>ex vivo</i> Artificial Pancreas

Diabetes is a serious worldwide epidemic that affects a growing portion of the population. While the most common method for testing blood glucose levels involves finger pricking, it is painful and inconvenient for patients. The authors test a non-invasive method to measure glucose levels from diabetic patients, and investigate whether the method is clinically accurate and universally applicable.

Read More...

Large-scale brain network connectivity under anxiety induced by naturalistic story listening

Chang et al. | Jun 03, 2026

Large-scale brain network connectivity under anxiety induced by naturalistic story listening

This study found that anxiety induced by a suspenseful story increased communication between the brain’s salience, default mode, and central executive networks, with the central executive network acting as a bridge during peak tension. These findings suggest that anxiety alters large-scale brain connectivity patterns and may help inform future diagnostic tools and personalized treatments for anxiety disorders.

Read More...

Importance of pay on job satisfaction

Ravi et al. | Mar 25, 2025

Importance of pay on job satisfaction

Pay is a widely debated factor in workplace motivation, influencing both incentives and job satisfaction. This work analyzed employee reviews across various industries to examine the relationship between pay importance and job satisfaction. Findings suggest that job satisfaction decreases as the importance of pay increases, particularly in construction, food, and finance industries, as well as among entry-level and experienced workers, though the results were not statistically significant.

Read More...