In this study, the authors conduct a bibliometric analysis to understand the recent growth in and current state of peripheral nerve regeneration research. They also explored potential future studies.
Read More...A bibliometric analysis of the use of biomimetic silk conduits for treating peripheral nerve injuries
In this study, the authors conduct a bibliometric analysis to understand the recent growth in and current state of peripheral nerve regeneration research. They also explored potential future studies.
Read More...Phytochemical Analysis of Amaranthus spinosus Linn.: An in vitro Analysis
Mainstream cancer treatments, which include radiotherapy and chemotherapeutic drugs, are known to induce oxidative damage to healthy somatic cells due to the liberation of harmful free radicals. In order to avert this, physiological antioxidants must be complemented with external antioxidants. Here the authors performed a preliminary phytochemical screen to identify alkaloids, saponins, flavonoids, polyphenols, and tannins in all parts of the Amaranthus spinosus Linn. plant. This paper describes the preparation of this crude extract and assesses its antioxidant properties for potential use in complementary cancer treatment.
Read More...RNAi-based Gene Therapy Targeting ZGPAT Promotes EGF-dependent Wound Healing
Wound-healing involves a sequence of events, such as inflammation, proliferation, and migration of different cell types like fibroblasts. Zinc Finger CCCH-type with G-Patch Domain Containing Protein (ZGPAT), encodes a protein that has its main role as a transcription repressor by binding to a specific DNA sequence. The aim of the study was to find out whether inhibiting ZGPAT will expedite the wound healing process by accelerating cell migration. This treatment strategy can provide a key to the development of wound healing strategies in medicine and cellular biology.
Read More...Modular mimics of neuroactive alkaloids - design, synthesis, and cholinesterase inhibitory activity of rivastigmine analogs
Naturally occurring neuroactive alkaloids are often studied for their potential to treat Neurological diseases. This team of students study Rivastigmine, a potent cholinesterase inhibitor that is a synthetic analog of physostigmine, which comes from the Calabar bean plant Physostigma venenosum. By comparing the effects of optimized synthetic analogs to the naturally occurring alkaloid, they determine the most favorable analog for inhibition of acetylcholinesterase (AChE), the enzyme that breaks down the neurotransmitter acetylcholine (ACh) to terminate neuronal transmission and signaling between synapses.
Read More...The Effect of Radiant Energy on Radish Seed Germination
Simon and colleagues test how exposure to microwaves affect radish seed germination, either microwaving seeds for ninety seconds or four minutes prior to planting. Surprisingly, the authors found that seeds microwaved for four minutes exhibited 150% increased germination as compared to controls. The authors hypothesize that breakdown of the radish seed coat when exposed to heat may allow seedlings to sprout more efficiently.
Read More...Cell cytotoxicity and pro-apoptosis on MCF-7 cells using polyherbal formulation, MAT20
The purpose of this study was to test the anti-cancer properties and pro-apoptotic effects of the polyherbal formulation MAT20 as a complementary treatment. Moringa oleifera (Moringa), Phyllanthus emblica (Amla) and Ocimum sanctum (Tulsi), these 3 herbs were used to formulate MAT20, which contain phytochemicals that are known to display anti-cancer properties. In this study, we hypothesized that MCF-7 breast cancer cells treated with MAT20 would show increased cytotoxicity compared to its individual plant extracts.
Read More...Primary source of dietary protein is correlated with differences in the intestinal microbiome diversity
We know relatively little about how vegan diets and non-vegan diets compare when it comes to the gut microbiome. Gollamudi and Gollamudi tackle this challenge by investigating how changes in a participant's diet affected the diversity of their intestinal microbiome.
Read More...Genetic algorithm based features selection for predicting the unemployment rate of India
The authors looked at using genetic algorithms to look at the Indian labor market and what features might best explain any variation seen. They found that features such as economic growth and household consumption, among others, best explained variation.
Read More...Thermoelectric cooling in greenhouses: Implications for small-holder production
The authors set to test a system that would help with the dehumidification and overall management of greehouses.
Read More...Analysis of ultraviolet light as a bactericide of gram-negative bacteria in Cladophora macroalgae extracts
Here, the authors sought to use Cladophora macroalgae as a possible antibiotic to address the growing threat of antibiotic resistance in pathogenic bacteria. However, when they observed algae extracts to be greatly contaminated with gram-negative bacteria, they adapted to explore the ability to use ultraviolet light as a bactericide. They found that treatment with ultraviolet light had a significant effect.
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