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pH-dependent drug interactions with acid reducing agents

Lin et al. | Nov 12, 2024

pH-dependent drug interactions with acid reducing agents
Image credit: The authors

Some cancer treatments lose efficacy when combined with treatments for excessive stomach acid, due to the changes in the stomach environment caused by the stomach acid treatments. Lin and Lin investigate information on oral cancer drugs to see what information is available on interactions of these drugs.

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Firearm-purchase laws that limit the number of guns on the market reduce gun homicides in the South Side of Chicago

Krishnan et al. | Jan 24, 2022

Firearm-purchase laws that limit the number of guns on the market reduce gun homicides in the South Side of Chicago

Gun violence has been a serious issue in the South Side of Chicago for a long time. To intervene, regulators have passed legislation they hoped to curb -if not completely eradicate- the issue. However, there is little analysis done on how effective the various laws have been at reducing gun violence. Here the authors explore the association between firearm purchase laws passed between 1993-2018 and the incidence of gun homicide in Chicago's South Side. Their analysis suggests that some laws have been more effective than others, while some might have exacerbated the issue. However, they do not consider other contributing factors, which makes it difficult to prove causation without further investigation.

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Determining the Hubble constant through the analysis of Abell clusters

Lee et al. | Sep 28, 2026

Determining the Hubble constant through the analysis of  Abell clusters
Image credit: NASA Hubble Space Telescope

Galaxy clusters offer several advantages for measuring H0 compared to traditional methods, such as Cepheid variables or Type Ia supernovae. Unlike individual stars or supernovae, clusters are less affected by local variations in stellar population or interstellar medium properties, providing a more stable and consistent measure over large cosmological distances. This work proposes using galaxy clusters as an alternative method for determining the H0. It provides an independent perspective on the H0 debate and contribute to ongoing efforts to reconcile the differing values obtained from the other two measurements.

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