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Identification of a Free Radical Scavenger as an Additive for Lung Transplant Preservation Solution to Inhibit Coagulative Necrosis and Extend Organ Preservation

Ganesh et al. | Feb 12, 2015

Identification of a Free Radical Scavenger as an Additive for Lung Transplant Preservation Solution to Inhibit Coagulative Necrosis and Extend Organ Preservation

During transfer of organs from a donor to a patient, the organs deteriorate in part due to damage by free radicals. Application of antioxidant solutions could extend organ preservation times. The authors found that vitamin E and butylated hydroxytoluene seemed to be most effective in arresting cell damage of a bovine lung.

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Leveraging transfer learning with convolutional neural networks for cardiovascular disease detection

Chen et al. | May 25, 2026

Leveraging transfer learning with convolutional neural networks for cardiovascular disease detection
Image credit: Stephen Andrews

This study shows the efficacy of leveraging transfer learning, specifically from residual networks, to detect CVDs and possible signs of CVDs. The findings indicate that leveraging transfer learning from residual networks alongside medical professionals is a highly promising approach for CVD detection and diagnosis, warranting further investigation.

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VISTA inhibitor CA170 combined with KRAS vaccine enhances immune response in lung cancer

Giglio et al. | Mar 16, 2026

VISTA inhibitor CA170 combined with <i>KRAS</i> vaccine enhances immune response in lung cancer
Image credit: Robina Weermeijer

Here the authors investigated a combination therapy to target the Kirsten rat sarcoma viral oncogene homolog mutation in lung cancer, by analyzing publicly available data. Their findings indicate that the combination therapy of CA170 and Kvax enhances helper T cell function and improves cytotoxic T lymphocyte infiltration, while Kvax alone drives plasma and memory B cell proliferation.

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Tree-Based Learning Algorithms to Classify ECG with Arrhythmias

Sun et al. | Apr 23, 2025

Tree-Based Learning Algorithms to Classify ECG with Arrhythmias

Arrhythmias vary in type and treatment, and ECGs are used to detect them, though human interpretation can be inconsistent. The researchers tested four tree-based algorithms (gradient boosting, random forest, decision tree, and extra trees) on ECG data from over 10,000 patients.

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