Browse Articles

Utilizing 25-Hydroxyvitamin D3 to prevent the appearance of diabetic-like phenotypes in Drosophila melanogaster

Zaverchand et al. | Sep 20, 2021

Utilizing 25-Hydroxyvitamin D3 to prevent the appearance of diabetic-like phenotypes in Drosophila melanogaster

This study aimed to assess the role of 25-hydroxyvitamin D3 solution, at varying concentrations, in protecting vertical transmission of diabetic-like phenotypes. We hypothesized that the highest concentration of vitamin D solution (55 ng/mL) would be most effective in having a protective role. The results indicated that the hypothesis was partially supported; overall, all three concentrations of the vitamin D solution administered to the flies reared on HSDs had a protective effect, to varying extents.

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Mitigation of ultraviolet solar radiation involving calcite

Nare et al. | Oct 10, 2026

Mitigation of ultraviolet solar radiation involving calcite

This study tested whether calcite, a safe and naturally occurring mineral, can block ultraviolet (UV) radiation when used in solar geoengineering. Students launched a high‑altitude balloon carrying UV sensors and calcite‑coated sheets to measure how much UV light passed through different calcite concentrations. Their results showed that calcite significantly reduces UV transmission, suggesting it may be a promising material for future stratospheric aerosol injection to help mitigate climate change.

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Modular mimics of neuroactive alkaloids - design, synthesis, and cholinesterase inhibitory activity of rivastigmine analogs

Yu et al. | Sep 12, 2022

Modular mimics of neuroactive alkaloids - design, synthesis, and cholinesterase inhibitory activity of rivastigmine analogs

Naturally occurring neuroactive alkaloids are often studied for their potential to treat Neurological diseases. This team of students study Rivastigmine, a potent cholinesterase inhibitor that is a synthetic analog of physostigmine, which comes from the Calabar bean plant Physostigma venenosum. By comparing the effects of optimized synthetic analogs to the naturally occurring alkaloid, they determine the most favorable analog for inhibition of acetylcholinesterase (AChE), the enzyme that breaks down the neurotransmitter acetylcholine (ACh) to terminate neuronal transmission and signaling between synapses.

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Male Feminization of the Common Pillbug Armadillidium vulgare by Wolbachia bacteria

Ramanan et al. | Jun 30, 2024

Male Feminization of the Common Pillbug <i>Armadillidium vulgare</i> by <i>Wolbachia</i> bacteria
Image credit: Ramanan et al. 2024

Wolbachia pipientis (Wolbachia) is a maternally inherited endosymbiotic bacterium that infects over 50% of arthropods, including pillbugs, and acts as a reproductive parasite in the host. In the common terrestrial pillbug Armadillidium vulgare (A. vulgare), Wolbachia alters the sex ratio of offspring through a phenomenon called feminization, where genetic males develop into reproductive females. Previous studies have focused on the presence or absence of Wolbachia as a sex ratio distorter in laboratory cultured and natural populations mainly from sites in Europe and Japan. Our three-year study is the first to evaluate the effects of the Wolbachia sex ratio distorter in cultured A. vulgare offspring in North America. We asked whether Wolbachia bacteria feminize A. vulgare isopod male offspring from infected mothers and if this effect can be detected in F1 offspring by comparing the male/female offspring ratios. If so, the F1 offspring ratio should show a higher number of females than males compared to the offspring of uninfected mothers. Over three years, pillbug offspring were cultured from pregnant A. vulgare females and developed into adults. We determined the Wolbachia status of mothers and counted the ratios of male and female F1 progeny to determine feminization effects. In each year sampled, significantly more female offspring were born to Wolbachia-infected mothers than those from uninfected mothers. These ratio differences suggest that the Wolbachia infection status of mothers directly impacts the A. vulgare population through the production of reproductive feminized males, which in turn provides an advantage for further Wolbachia transmission.

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Examining effects of E. muscae on olfactory function in D. melanogaster

Friedman et al. | Jul 08, 2021

Examining effects of <em>E. muscae</em> on olfactory function in <em>D. melanogaster</em>

In this article, the authors investigate the effects of fungus E. muscae on fruit fly behavior. More specifically, they investigate whether this fungus affects olfaction. Their findings contribute to a broader set of studies seeking to understand how host's central nervous systems can be affected by infections.

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AeroPurify: Autonomous air filtration UAV using real-time 3-D Monte Carlo gradient search

Kadakia et al. | Sep 01, 2025

AeroPurify: Autonomous air filtration UAV using real-time 3-D Monte Carlo gradient search
Image credit: Ian Usher

Here the authors present an autonomous drone air filtration system that uses a novel algorithm, the gradient ascent ML particle filter (GA/MLPF), to efficiently locate and mitigate outdoor air pollution. They demonstrate that their GA/MLPF algorithm is significantly more efficient than the conventional gradient ascent algorithm, reducing both the time and number of waypoints needed to find the source of pollution.

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Suppress that algae: Mitigating the effects of harmful algal blooms through preemptive detection & suppression

Natarajan et al. | Jul 17, 2023

Suppress that algae: Mitigating the effects of harmful algal blooms through preemptive detection & suppression
Image credit: Sharanya Natarajan

A bottleneck in deleting algal blooms is that current data section is manual and is reactionary to an existing algal bloom. These authors made a custom-designed Seek and Destroy Algal Mitigation System (SDAMS) that detects harmful algal blooms at earlier time points with astonishing accuracy, and can instantaneously suppress the pre-bloom algal population.

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The Prevalence of Brain-Eating Roundworm Baylisascaris procyonis in Merrick County, Nebraska

Reeves et al. | Sep 20, 2018

The Prevalence of Brain-Eating Roundworm <i>Baylisascaris procyonis</i> in Merrick County, Nebraska

The authors investigated an important parasite-host relationship between the raccoon roundworm and the raccoon to understand how parasite prevalence is affected by location. They found that the parasite infection was more prevalent in raccoons found closer to human dwellings, though the number of roundworm eggs was not significantly different. These results are important human health, since roundworm infection is lethal to humans and can be transmitted from raccoons to humans - the authors suggest that more research into this parasite and awareness of its prevalence is needed to prevent disease.

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