The Effects of Ezetimibe on Triglyceride and Alanine Transaminase Reduction in Drosophila Melanogaster Model of Nonalcoholic Fatty Liver Disease (NAFLD)
Nonalcoholic Fatty Liver Disease (NAFLD) is a condition where a surplus of triglycerides or fat are present in the liver. In this study, ezetimibe, a cholesterol lowering drug, was used to treat flies modeling NAFLD. Compared to the coconut oil fed flies that were transferred to the control medium, the flies transferred to the control medium treated with ezetimibe showed a decrease in their triglyceride and alanine transaminase level.
Read More...The effects of a high-sucrose diet on the survival of Drosophila melanogaster from a bacterial infection
Excess sucrose consumption has been associated with several health problems, including inflammation and potential negative effects on immune function. However, the exact relationship between sucrose intake and immunity remains unclear, especially during bacterial infections. This study examined how sucrose intake affected the survival of fruit flies following oral infection with the bacterial pathogen Serratia marcescens.
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