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The Effects of Altered Microbiome on Caenorhabditis elegans Egg Laying Behavior

Gohari et al. | Aug 12, 2019

The Effects of Altered Microbiome on <em>Caenorhabditis elegans</em> Egg Laying Behavior

Since the discovery that thousands of different bacteria colonize our gut, many of which are important for human wellbeing, understanding the significance of balancing the different species on the human body has been intensely researched. Untangling the complexity of the gut microbiome and establishing the effect of the various strains on human health is a challenge in many circumstances, and the need for simpler systems to improve our basic understanding of microbe-host interactions seems necessary. C. elegans are a well-established laboratory animal that feed on bacteria and can thus serve as a less complex system for studying microbe-host interactions. Here the authors investigate how the choice of bacterial diet affects worm fertility. The same approach could be applied to many different outcomes, and facilitate our understanding of how the microbes colonizing our guts affect various bodily functions.

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The Effect of Delivery Method, Speaker Demographics, and Physical Environment on the Engagement Level of Older Adults

Seides et al. | May 24, 2015

The Effect of Delivery Method, Speaker Demographics, and Physical Environment on the Engagement Level of Older Adults

With an increasing older adult population and rapid advancements in technology, it is important that senior citizens learn to use new technologies to remain active in society. A variety of factors on learning were investigated through surveys of senior citizens. Older adults preferred an interactive lesson style, which also seemed to help them retain more course material.

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Correlating inlet gas composition to conversion efficiency in plasma-assisted landfill gas reforming

Kim et al. | Jun 28, 2025

Correlating inlet gas composition to conversion efficiency in plasma-assisted landfill gas reforming

The escalating crisis of climate change, driven by the accumulation of greenhouse gases from human activities, demands urgent and innovative solutions to curb rising global temperatures. Plasma-based methane (CH4) and carbon dioxide (CO2) reforming offers a promising pathway for carbon capture and the sustainable production of hydrogen fuel and syngas components. To advance this technology, particularly in terms of energy efficiency and selectivity, it is essential to enhance the conversion efficiencies of CO2 and CH4.

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Development of selective RAC1/KLRN inhibitors

Kubrat Neczaj-Hruzewicz et al. | Nov 04, 2024

Development of selective RAC1/KLRN inhibitors

Kalirin is a guanine nucleotide exchange factor (GEF) for the GTPase RAC1, linked to schizophrenia and Alzheimer’s Disease. It plays a crucial role in synaptic plasticity by regulating dendritic spine formation and actin cytoskeleton remodeling, which are essential for creating new synapses. Authors developed two novel compounds targeting kalirin, confirming that predictive modeling can indicate biological activity.

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