Browse Articles

Deciphering correlation and causation in risk factors for heart disease with Mendelian randomization

Singh et al. | Feb 08, 2023

Deciphering correlation and causation in risk factors for heart disease with Mendelian randomization
Image credit: Robina Weermeijer

Here, seeking to identify the risk of coronary artery disease (CAD), a major cause of cardiovascular disease, the authors used Mendelian randomization. With this method they identified several traits such as blood pressure readings, LDL cholesterol and BMI as significant risk factors. While other traits were not found to be significant risk factors.

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Application of gene therapy for reversing T-cell dysfunction in cancer

Hyun Lee et al. | Aug 25, 2022

Application of gene therapy for reversing T-cell dysfunction in cancer

Since cancer cells inhibit T-cell activity, the authors investigated a method to reverse T-cell disfunction with gene therapy, so that the T-cells would become effective once again in fighting cancer cells. They used the inhibition of proprotein convertases (PCSK1) in T cells and programmed death-ligand 1 (CD274) in cancer cells. They observed the recovery of IL-2 expression in Jurkat cells, with increased recovery noted in a co-culture sample. This study suggests a novel strategy to reactivate T cells.

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Conversion of Mesenchymal Stem Cells to Cancer-Associated Fibroblasts in a Tumor Microenvironment: An in vitro Study

Ramesh et al. | Feb 18, 2020

Conversion of Mesenchymal Stem Cells to Cancer-Associated Fibroblasts in a Tumor Microenvironment: An <em>in vitro</em> Study

Mesenchymal stem cells(MSCs) play a role in tumor formation by differentiating into cancer associated fibroblasts (CAFs) which enable metastasis of tumors. The process of conversion of MSCs into CAFs is not clear. In this study, authors tested the hypothesis that cancers cells secrete soluble factors that induce differentiation by culturing bone marrow mesenchymal stem cells in media conditioned by a breast cancer cell line.

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Environmental, Social, and Governance (ESG) Standards and Financial Performance in Vietnam’s Media Sector

Nguyen et al. | Jul 29, 2026

Environmental, Social, and Governance (ESG) Standards and Financial Performance in Vietnam’s Media Sector
Image credit: Nguyen, Tran, Pham, and Nguyen

In this study, the authors examine the relationship between ESG (Environmental, Social, and Governance) factors on financial performance of Vietnamese media companies, as measured by ROA and ROE. They find that ESG is positively correlated with financial performance, as is sales growth. They also find that financial leverage is negatively correlated with ROA. Overall, this is a quality study, although the methods section requires more detail.

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A 3D printed triboelectric nanogenerator for bridge vibration energy harvesting and sensing

Walavalkar et al. | Jul 19, 2026

A 3D printed triboelectric nanogenerator for bridge vibration energy harvesting and sensing
Image credit: Jakub Żerdzicki

This study strongly illustrates that optimizing 3D printing parameters would enhance a triboelectric nanogenerator's performance. The design improvements substantiate the potential of optimized, 3D-printed TENGs for developing scalable, cost-effective solutions for powering low-energy electronics, particularly in applications such as structural health monitoring.

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