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One important factor that contributes to human cancers is accumulated damage to cells' DNA due to the oxidative stress caused by free radicals. In this study, the authors investigate the effects of several different tea leaf extracts on oxidative stress in cultured human prostate cells to see if antioxidants in the tea leaves could help protect cells from this type of DNA damage. They found that all four types of tea extract (as well as direct application of the antioxidant EGCG) improved the outcomes for the cultured cells, with white tea extract having the strongest effect. This research suggests that tea extracts and the antioxidants that they contain may have applications in the treatment of the many diseases associated with cellular DNA damage, including cancer.

The authors test the activity of two purified human alcohol detoxification enzymes, alcohol dehydrogenase and aldehyde dehydrogenase.

Microplastics (MPs) are inorganic material that have been observed within items destined for human consumption, including water, and may pose a potential health hazard. Here we estimated the average amount of MPs junior high students and teachers consumed from different water sources and determined whether promoting awareness of microplastic (MP) exposure influenced choice of water source and potential MPs consumed.

Poor air quality is associated with negative effects on human health but can be difficult to measure in an accurate and cost-effective manner. The authors design and test a monitor for measuring indoor air quality using low-cost components.

Trihalomethanes, probable human carcinogens, are commonly found disinfection by-products (DBPs) in public water systems (PWS). The authors investigated the correlation between trihalomethane concentrations and socioeconomic factors in New York State, finding a negative correlation between median household income and trihalomethane concentrations. The inverse association between trihalomethanes and household income may indicate socioeconomic disparity regarding drinking water quality and the need for improved efforts to assist small- and medium-sized community water systems to lower DBP levels in New York State.

The authors compare RNA expression profiles across three human cell types following infection with MERS-CoV

Seeking to investigate the effects of ambient pollutants on human respiratory health, here the authors used machine learning to examine asthma in Lost Angeles County, an area with substantial pollution. By using machine learning models and classification techniques, the authors identified that nitrogen dioxide and ozone levels were significantly correlated with asthma hospitalizations. Based on an identified seasonal surge in asthma hospitalizations, the authors suggest future directions to improve machine learning modeling to investigate these relationships.

Since the discovery that thousands of different bacteria colonize our gut, many of which are important for human wellbeing, understanding the significance of balancing the different species on the human body has been intensely researched. Untangling the complexity of the gut microbiome and establishing the effect of the various strains on human health is a challenge in many circumstances, and the need for simpler systems to improve our basic understanding of microbe-host interactions seems necessary. C. elegans are a well-established laboratory animal that feed on bacteria and can thus serve as a less complex system for studying microbe-host interactions. Here the authors investigate how the choice of bacterial diet affects worm fertility. The same approach could be applied to many different outcomes, and facilitate our understanding of how the microbes colonizing our guts affect various bodily functions.

Inherent bias is often the unconscious driver of human behavior, and the first step towards overcoming these biases is our awareness of them. In this article the authors investigate whether race, gender or species affect the choice of charity by middle class Spaniards. Their conclusions serve as a starting point for further studies that could help charities refine their campaigns in light of these biases effectively transcending them or taking advantage of them to improve their fundraising attempts.

Control of voluntary and involuntary movements is one of the most important aspects of human neurological function, but the mechanisms of motor control are not completely understood. In this study, the authors use transcranial magnetic stimulation (TMS) to stimulate a portion of the motor cortex while subjects performed either discrete (e.g. throwing) or rhythmic (e.g. walking) movements. By recording electrical activity in the muscles during this process, the authors showed that motor evoked potentials (MEPs) measured in the muscles during TMS stimulation are larger in amplitude for discrete movements than for rhythmic movements. Interestingly, they also found that MEPs during transitions between rhythmic and discrete movements were nearly identical and larger in amplitude than those recorded during either rhythmic or discrete movements. This research provides important insights into the mechanisms of neurological control of movement and will serve as the foundation for future studies to learn more about temporal variability in neural activity during different movement types.