In this study, the authors hypothesized that closed-circuit television images could be stored with improved resolution by using enhanced deep residual (EDSR) networks.
Read More...Deep residual neural networks for increasing the resolution of CCTV images
In this study, the authors hypothesized that closed-circuit television images could be stored with improved resolution by using enhanced deep residual (EDSR) networks.
Read More...Socio-economic and awareness correlates of physical activity of government school children in India
Here, based on the identified importance of physical activity in the development of young children, the authors investigated the effects of socioeconomic factors on the amount of physical activity of government-school children in India. They found significant differences between boys and girls, rural and urban, and children who were encouraged to exercise and those who were not. Overall, they suggest that their findings point to the important role of schools and communities in promoting healthy active lifestyles for developing children.
Read More...Development of a novel machine learning platform to identify structural trends among NNRTI HIV-1 reverse transcriptase inhibitors
With advancements in machine learning a large data scale, high throughput virtual screening has become a more attractive method for screening drug candidates. This study compared the accuracy of molecular descriptors from two cheminformatics Mordred and PaDEL, software libraries, in characterizing the chemo-structural composition of 53 compounds from the non-nucleoside reverse transcriptase inhibitors (NNRTI) class. The classification model built with the filtered set of descriptors from Mordred was superior to the model using PaDEL descriptors. This approach can accelerate the identification of hit compounds and improve the efficiency of the drug discovery pipeline.
Read More...Analysis of the effects of positive ions and boundary layer temperature at various hypersonic speeds on boundary layer density
This study's goal was to identify the Mach numbers for which electrostatic drag and heat transfer manipulation would be most applicable inside the stratosphere. The experiments were conducted using computational fluid dynamics software. The study demonstrated that, on average, higher Mach speeds resulted in a considerably higher potential decrease in density. The study highlights that further research on the surface charge method is warranted to explore higher hypersonic speeds within the stratosphere.
Read More...Investigation of Everyday Locations for Antibiotic-Resistant Bacteria in Cambridge, Massachusetts
In this study, the authors investigate whether antibiotic-resistant bacteria can be found in everyday locations. To do this, they collected samples from multiple high-trafficked areas in Cambridge, MA and grew them in the presence and absence of antibiotics. Interestingly, they grew bacterial colonies from many locations' samples, but not all could grow in the presence of ampicillin. These findings are intriguing and relevant given the rising concern about antibiotic-resistant bacteria.
Read More...Assessing Materials’ Short-term Effectiveness on Controlling Zebra Mussel (Dreissena polymorpha) Attachment
Zebra mussels are an aquatic invasive species. They attach to essential industrial structures and harm the native ecosystem, costing millions of dollars each year to control. This study explored the effectiveness of two nontoxic materials (Sharklet & Netminder) in combating zebra mussel attachment.
Read More...The relationship between multilingualism and visual imagery: Investigating aphantasia using the VVIQ
The authors looked at the correlation between being able to speak more than one language (multilingualism) and visual imagery. They found multilingual individuals had higher visual imagery as measured by the VVIQ.
Read More...Mechanism and cytotoxicity of A1874 proteolysis targeting chimera on CT26 colon carcinoma cell line
This study investigates the effects of the PROTAC compound A1874 on CT26 colon carcinoma cells, focusing on its ability to degrade the protein BRD4 and reduce cell viability. While A1874 had previously shown effectiveness in other colon cancer cell lines, its impact on CT26 cells was unknown.
Read More...Investigating AlphaFold’s handling of nanobody-antigen complex prediction
Predicting antibody structures and antibody-antigen complexes using AlphaFold
Read More...Slowing ice melting from thermal radiation using sustainable, eco-friendly eggshells
The authors looked at the ability of eggshells to slow ice melting. They found that eggshells were able to increase ice melting time when crushed showing that they were an effective thermal barrier.
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