In this study, the authors address the concerns of heavy metal contamination in industrial and feedlot water waste. They test whether added probiotics are capable of taking up heavy metals in water to attenuate pollution.
Read More...Probiotic biosorption as a way to remove heavy metal in seawater
In this study, the authors address the concerns of heavy metal contamination in industrial and feedlot water waste. They test whether added probiotics are capable of taking up heavy metals in water to attenuate pollution.
Read More...Potential Multifunctional Agents for Dual Therapy of Age-Related and Associated Diseases: Alzheimer’s Disease and Type 2 Diabetes Mellitus
Studies show an age-related link between Alzheimer’s Disease and Type 2 Diabetes Mellitus with oxidative stress a characteristic of both. Here, methanolic fractionations and extracts of four Ayurvedic plants were assessed for their protective abilities using a number of in vitro assays. Extracts inhibited oxidative stress and reduced activity of key enzymes involved in the pathogenesis of both diseases in neuroblastoma cells.
Read More...Cell cytotoxicity and pro-apoptosis on MCF-7 cells using polyherbal formulation, MAT20
The purpose of this study was to test the anti-cancer properties and pro-apoptotic effects of the polyherbal formulation MAT20 as a complementary treatment. Moringa oleifera (Moringa), Phyllanthus emblica (Amla) and Ocimum sanctum (Tulsi), these 3 herbs were used to formulate MAT20, which contain phytochemicals that are known to display anti-cancer properties. In this study, we hypothesized that MCF-7 breast cancer cells treated with MAT20 would show increased cytotoxicity compared to its individual plant extracts.
Read More...Primary source of dietary protein is correlated with differences in the intestinal microbiome diversity
We know relatively little about how vegan diets and non-vegan diets compare when it comes to the gut microbiome. Gollamudi and Gollamudi tackle this challenge by investigating how changes in a participant's diet affected the diversity of their intestinal microbiome.
Read More...Deciphering correlation and causation in risk factors for heart disease with Mendelian randomization
Here, seeking to identify the risk of coronary artery disease (CAD), a major cause of cardiovascular disease, the authors used Mendelian randomization. With this method they identified several traits such as blood pressure readings, LDL cholesterol and BMI as significant risk factors. While other traits were not found to be significant risk factors.
Read More...The Effects of Micro-Algae Characteristics on the Bioremediation Rate of Deepwater Horizon Crude Oil
Environmental disasters such as the Deepwater Horizon oil spill can be devastating to ecosystems for long periods of time. Safer, cheaper, and more effective methods of oil clean-up are needed to clean up oil spills in the future. Here, the authors investigate the ability of natural ocean algae to process crude oil into less toxic chemicals. They identify Coccochloris elabens as a particularly promising algae for future bioremediation efforts.
Read More...Cocktail therapy to inhibit multispecies biofilm in cystic fibrosis patients
Here, recognizing the important role of bacterial biofilms in many life-threatening chronic infections, the authors investigated the effectiveness of a combination treatment on biofilms composed of up to three different common species within the lungs of cystic fibrosis patients with computational analysis. They found that a triple cocktail therapy targeting three different signaling pathways has significant potential as both a treatment and prophylaxis.
Read More...Combined Progestin-Estrogenic Contraceptive Pills May Promote Growth in Crop-Plants
Ethinyl estradiol and progestin norgestrel are commonly present in contraceptive tablets and it is unknown how they affect the environment. In this study, the authors investigate the role that ethinyl estradiol and progestin norgestrel have on the growth of flowering plants. The percentage germination, embryonic and adventitious tissue proliferation, root length, and shoot length were measured in V. radiata and T. aestivum treated with each compound and results demonstrate that ethinyl estradiol and progestin norgestrel can induce growth in both plants at certain concentrations. These findings have important implications as societal use of chemicals increases and more make their way into the environment.
Read More...Application of gene therapy for reversing T-cell dysfunction in cancer
Since cancer cells inhibit T-cell activity, the authors investigated a method to reverse T-cell disfunction with gene therapy, so that the T-cells would become effective once again in fighting cancer cells. They used the inhibition of proprotein convertases (PCSK1) in T cells and programmed death-ligand 1 (CD274) in cancer cells. They observed the recovery of IL-2 expression in Jurkat cells, with increased recovery noted in a co-culture sample. This study suggests a novel strategy to reactivate T cells.
Read More...The effects of early probiotic supplementation on the germination of Arabidopsis thaliana
The use of fertilizers is associated with an increase in soil degradation, which is predicted to lead to a decrease in crop production within the next decade. Thus, it is critical to find solutions to support crop production to sustain the robust global population. In this study, the authors investigate how probiotic bacteria, like Rhizobium leguminosarum, Bacillus subtilis and Pseudomonas fluorescens, can impact the growth of Arabidopsis thaliana when applied to the seeds.They hypothesized that solutions with multiple bacterial species compared to those with only a single bacterial species would promote seed germination more effectively.
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