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Reducing tremors in LRRK2-G2019S genetically-mutated Parkinson’s flies with a lovastatin–levodopa combination

Foell et al. | Nov 11, 2026

Reducing tremors in LRRK2-G2019S genetically-mutated Parkinson’s flies with a lovastatin–levodopa combination
Image credit: Authors

Here the authors investigated alternative treatments for Parkinson's disease tremors, this study tested whether replacing the traditional carbidopa component with lovastatin in a levodopa combination would improve symptom reduction in a Drosophila melanogaster model. The findings revealed that the lovastatin–levodopa combination was more optimal at reducing tremors than the standard treatment, pointing to a potentially superior therapeutic approach for future investigation.

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A HOG feature extraction and CNN approach to Parkinson’s spiral drawing diagnosis

Tripathi et al. | Aug 09, 2024

A HOG feature extraction and CNN approach to Parkinson’s spiral drawing diagnosis

Parkinson’s disease (PD) is a prevalent neurodegenerative disorder in the U.S., second only to Alzheimer’s disease. Current diagnostic methods are often inefficient and dependent on clinical exams. This study explored using machine and deep learning to enhance PD diagnosis by analyzing spiral drawings affected by hand tremors, a common PD symptom.

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