This study used single-cell RNA sequencing to examine whether B cells can predict response to pembrolizumab and radiation therapy in patients with triple-negative breast cancer.
Read More...B cell dynamics as predictive markers in triple-negative breast cancer treated with Pembrolizumab & radiation
This study used single-cell RNA sequencing to examine whether B cells can predict response to pembrolizumab and radiation therapy in patients with triple-negative breast cancer.
Read More...Transfer Learning with Convolutional Neural Network-Based Models for Skin Cancer Classification
Skin cancer is a common and potentially deadly form of cancer. This study’s purpose was to develop an automated approach for early detection for skin cancer. We hypothesized that convolutional neural network-based models using transfer learning could accurately differentiate between benign and malignant moles using natural images of human skin.
Read More...The precision of machine learning models at classifying autism spectrum disorder in adults
Autism spectrum disorder (ASD) is hard to correctly diagnose due to the very subjective nature of diagnosing it: behavior analysis. Due to this issue, we sought to find a machine learning-based method that diagnoses ASD without behavior analysis or helps reduce misdiagnosis.
Read More...Alkaloids Detection in Commonly Found Medicinal Plants with Marquis Reagent
This study investigates the presence of alkaloids in a variety of medicinal plants using the Marquis reagent. They reveal some surprising results and how useful the Marquis reagent is.
Read More...Machine Learning Algorithm Using Logistic Regression and an Artificial Neural Network (ANN) for Early Stage Detection of Parkinson’s Disease
Despite the prevalence of PD, diagnosing PD is expensive, requires specialized testing, and is often inaccurate. Moreover, diagnosis is often made late in the disease course when treatments are less effective. Using existing voice data from patients with PD and healthy controls, the authors created and trained two different algorithms: one using logistic regression and another employing an artificial neural network (ANN).
Read More...Strain-selective in vitro and in silico structure activity relationship (SAR) of N-acyl β-lactam broad spectrum antibiotics
In this study, the authors investigate the antibacterial efficacy of penicillin G and its analogs amoxicillin, carbenicillin, piperacillin, cloxacillin, and ampicillin, against four species of bacteria. Results showed that all six penicillin-type antibiotics inhibit Staphylococcus epidermidis, Escherichia coli, and Neisseria sicca with varying degrees of efficacy but exhibited no inhibition against Bacillus cereus. Penicillin G had the greatest broad-spectrum antibacterial activity with a high radius of inhibition against S. epidermidis, E. coli, and N. sicca.
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