In this study, the effects of different sources of serum on growing mesenchymal stem cells are compared with the goal of identifying one more suitable for clinical use.
Read More...A comparison study in the expansion of human bone marrow mesenchymal stem cells
In this study, the effects of different sources of serum on growing mesenchymal stem cells are compared with the goal of identifying one more suitable for clinical use.
Read More...Inhibiting the ERK pathway and the TRPM7 ion channel in gastric and bladder cancer cells
In this work the authors investigate new possible treatment methods for gastric and bladder cancers. They specifically targeted the transient receptor potential cation subfamily M member 7 (TRPM7), an ion channel that plays an important role in the survival of both of these cancers, and extracellular regulated kinases (ERKs),which contributes to the carcinogenesis of many cancers including gastric cancer. As a result, the authors consider the effects of Ginsenoside Rd, NS8593, curcumin, and icariin , known to inhibit TRPM7 and ERK. The authors found that these treatments decrease proliferation and induce apoptosis in studies of gastric and bladder cancer cells.
Read More...Evaluation of hepatotoxicity from excessive acetaminophen: physiological and histological changes
The authors looked at how acetaminophen may cause liver damage by looking at both serum level markers of liver damage as well as liver pathology.
Read More...The effect of chondroitin sulfate on the development of plants grown in roadside soil
Heavy metal contamination from transportation can damage soil and vegetation by increasing oxidative stress, disrupting enzymes, and impairing photosynthesis. This study investigated whether chondroitin sulfate (CS) could reduce the harmful effects of contaminated roadside soil on plant growth by binding with metal ions.
Read More...A 1D model of ultrasound waves for diagnosing of hepatomegaly and cirrhosis
The authors created a 1D model to diagnose hepatomegaly and cirrhosis via ultrasound of the liver.
Read More...Comparing neural networks with a traditional method for identifying the vanishing points of surgical tools
Robot-assisted minimally invasive surgery (RMIS) benefits from increased precision and faster recovery, with force feedback from the surgical tool being critical for control. Researchers tested the use of neural networks for detecting the vanishing point of the tool, a key element for force feedback.
Read More...Evaluating the clinical applicability of neural networks for meningioma tumor segmentation on 3D MRI
Authors emphasize the challenges of manual tumor segmentation and the potential of deep learning models to enhance accuracy by automatically analyzing MRI scans.
Read More...Genetic underpinnings of the sex bias in autism spectrum disorder
Here, seeking to identify a possible explanation for the more frequent diagnosis of autism spectrum disorder (ASD) in males than females, they sought to investigate a potential sex bias in the expression of ASD-associated genes. Based on their analysis, they identified 17 ASD-associated candidate genes that showed stronger collective sex-dependent expression.
Read More...Identification of a core set of model agnostic mRNA associated with nonalcoholic steatohepatitis (NASH)
In this study, the authors analyze gene expression datasets to determine if there is a core set of genes dysregulated during nonalcoholic steatohepatitis.
Read More...Preliminary investigation of Allosauroidea facial integument and the evolution of theropod facial armor
The facial integument, or external skin tissues, were assessed on set of dinosaurs from the Allosauroidea clade to test whether dermal patterns served specific functions.
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