This study used single-cell RNA sequencing to examine whether B cells can predict response to pembrolizumab and radiation therapy in patients with triple-negative breast cancer.
Read More...B cell dynamics as predictive markers in triple-negative breast cancer treated with Pembrolizumab & radiation
This study used single-cell RNA sequencing to examine whether B cells can predict response to pembrolizumab and radiation therapy in patients with triple-negative breast cancer.
Read More...Study of PINN sensor layout in evaluating WSS with application to patient-specific carotid flow
Physics‑Informed Neural Networks (PINNs) offer a promising way to estimate blood‑flow behavior in arteries, especially near the vessel wall where traditional methods struggle. In this study, students tested how sensor density and placement affect PINN accuracy in modeling carotid artery flow and found that accuracy improves up to a moderate sensor density and depends strongly on how close sensors are placed to the arterial wall. Applying the optimized configuration to a patient‑specific carotid model produced velocity predictions closely matching computational fluid dynamics results, highlighting PINNs’ potential for future personalized cardiovascular assessment.
Read More...Global trends in total cholesterol by gender (1980-2018)
This study explores global trends in average total cholesterol levels among adults from 1980 to 2018, finding a significant decline in both men and women, with a sharper decrease among men. While these improvements likely reflect advances in public health and medical treatment, the persistent gender gap highlights the need for more targeted approaches to cardiovascular disease prevention.
Read More...Investigating the contribution of genetic risk factors to gastric cancer in Korean-ancestry populations
This project investigated whether previously identified genetic risk factors in non-Korean populations were associated with high gastric cancer incidence rates in Koreans.
Read More...How teaching style influences math learning: Comparing discovery and traditional instruction
This study compares traditional and discovery-based instructional methods in online middle school mathematics education. Findings show that discovery-based learning significantly improves students’ academic performance and attitudes, highlighting the value of inquiry-driven instruction for enhancing both understanding and motivation.
Read More...Analyzing the effects of genetic mutations in BRCA1, BRCA2, BARD1, and MLH1 in causing different cancers
This paper utilizes multiple publicly available cancer datasets to explore the abundance of different genetic dependencies across various cancer types. They explore this by looking at four genes highly associated with cancer and their genetic and pathogenic relationships.
Read More...Social and psychosocial factors associated with mood states among adolescents: A questionnaire-based study
The authors assess the relationship between supportive family environments and internalized stigma in adolescents.
Read More...Testing the Impact of a Geometric Curvature Variable on the Accuracy of Econometric Forecasting Models
Classical financial forecasting models often fail to capture the complex, nonlinear dynamics of the stock market. This study demonstrates that incorporating a single variable to represent the 'geometric curvature' of a time series dramatically improves the accuracy of standard econometric forecasts. Our findings highlight that geometric properties are a significant predictive factor, opening new avenues for more powerful financial modeling.
Read More...Upregulation of the AP-1 complex as a potential biomarker for Alzheimer’s disease (AD)
The relationship between meteorological factors and air quality in Washington D.C. metropolitan area
The authors studied the relationship between air quality and weather conditions (wind speed, precipitation, and temperature) in the Washington D.C. area.
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