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Exploring Interactions between PFAS (Per- and Polyfluoroalkyl Substances) and proteins

Lu-Yang et al. | May 16, 2026

Exploring Interactions between PFAS (Per- and Polyfluoroalkyl Substances) and proteins
Image credit: Authors

Here the authors investigated how the "forever chemical" perfluorooctanoic acid binds to bovine serum albumin (BSA) using computational software to simulate its potential impact on essential human plasma proteins. They identify a possible, high-energy binding configuration that could persistently impair protein functions, underscoring the critical need for further research into the long-term health risks of per- and poly-fluoroalkyl substances exposure.

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Examining the impact of consecutive losses on gambling: When do we decide to quit?

Kim et al. | Apr 28, 2026

Examining the impact of consecutive losses on gambling: When do we decide to quit?
Image credit: Kim, Cragun, and Kim

This article explored the question of when do people decide to stop gambling and further tries to extrapolate why people stop gambling at that point. Their study showed that people tend to quit gambling after 4 consecutive losses, significantly more than 1-3 consecutive losses or a win previous to quitting. They also found that participants commonly quit at a point value approximately 5 points greater than or less than their starting balance. The authors concluded that these results may be important in understanding how to cut down on excessive gambling or in creating policies that make it easier for people to disengage from gambling.

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VISTA inhibitor CA170 combined with KRAS vaccine enhances immune response in lung cancer

Giglio et al. | Mar 16, 2026

VISTA inhibitor CA170 combined with <i>KRAS</i> vaccine enhances immune response in lung cancer
Image credit: Robina Weermeijer

Here the authors investigated a combination therapy to target the Kirsten rat sarcoma viral oncogene homolog mutation in lung cancer, by analyzing publicly available data. Their findings indicate that the combination therapy of CA170 and Kvax enhances helper T cell function and improves cytotoxic T lymphocyte infiltration, while Kvax alone drives plasma and memory B cell proliferation.

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Quantifying natural recovery of dopamine deficits induced by chronic stress

Josyula et al. | Oct 27, 2025

Quantifying natural recovery of dopamine deficits induced by chronic stress
Image credit: Shawn Day

Here the authors investigated the natural recovery of stress-induced dopamine-related gene deficits in C. elegans by measuring the expression of cat-2 (dopamine biosynthesis) and sod-2 (oxidative stress) following exposure to starvation or hydrocortisone. They found that the reversibility of sod-2 and the expression of cat-2 were highly dependent on the type and severity of the stressor, suggesting that the body's natural ability to recover from dopamine dysfunction has biological limitations.

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