Browse Articles

Understanding and predicting cognitive decline in Alzheimer's disease

Antibiotic resistance is a growing global health threat, and one strategy to combat it is using bacteriophages to enhance the effectiveness of existing antibiotics. This study tested whether targeting the TolC protein in E. coli with the TLS bacteriophage would increase bacterial sensitivity to antibiotics.

The authors studied the impact of drying blood as a storage solution for space travel.

The authors looked at the effects of different treatments using flies with neurodevelopmental disorders.

The authors demonstrate computationally that two types of nanoplastics can bind to estrogen receptor beta and potentially disrupt endocrine systems.

The authors looked at how the presence of difference antibiotic resistance genes would influence antibiotic resistance in Staphylococcus aureus.

The authors employ computational protein design to identify a mini-protein with the potential to enhance binding of the tight junction protein, claudin-5, at the blood-blood barrier with therapeutic potential for neurodegenerative diseases.

This paper looks at the antibacterial and toxic effects of silver nanoparticles (AgNPs) on Escherichia coli bacteria and Drosophila melanogaster fruit flies. They modified the AgNPs size, concentration, and surface coating to determine the effects on each of the organisms. For both organisms, increased AgNP concentration demonstrated increased toxicity but particle size and surface coating had opposing effects.

The authors looked at how pharmacokinetics changed depending on the use of an in vitro or an in vivo model.

The authors looked at ways that seizures in patients with glioblastoma could be treated using C. elegans as a model system.