Browse Articles

Drosophila proteins as human surrogates for early drug discovery: Findings from detailed structural analysis

Shankar et al. | Oct 11, 2026

<i>Drosophila</i> proteins as human surrogates for early drug discovery: Findings from detailed structural analysis

This study examines the possibility of utilizing proteins from Drosophila melanogaster in early drug discovery. Structural and sequence analysis of five diverse Drosophila proteins and its human homologs were conducted. Drosophila proteins with high conservation of amino acids at functionally significant positions are better candidates for use as human surrogate in drug discovery efforts.

Read More...

Using machine learning to detect outliers of red clump stars

Meng et al. | Oct 10, 2026

Using machine learning to detect outliers of red clump stars

Machine learning offers a powerful way to analyze large astronomical datasets and identify stars with unusual properties. In this study, students used Extreme Gradient Boosting and Isolation Forest models to investigate why some red clump stars deviate from their expected luminosities. Their results show that stellar age plays a much stronger role than metallicity in driving luminosity variation, and the models successfully detected outlier stars that may affect distance measurements in galactic studies.

Read More...

Optimizing website performance: A comprehensive Google Lighthouse study on desktop and mobile modes

S. Al-Majidi et al. | Oct 02, 2026

Optimizing website performance: A comprehensive Google Lighthouse study on desktop and mobile modes

In this study, we examined the consistency and dependability of Google's Lighthouse tool for measuring website performance, accessibility, SEO, and best practices. Tests conducted on three websites showed that performance scores vary based on the testing mode and website complexity, while other audit categories stay constant. These results provide direction for researchers and developers by highlighting Lighthouse's benefits and drawbacks.

Read More...

Multi-omic analysis identifies mitochondrial dysfunction as a key feature of hypertrophic cardiomyopathy

Velu et al. | Sep 26, 2026

Multi-omic analysis identifies mitochondrial dysfunction as a key feature of hypertrophic cardiomyopathy

This study used multi-omic analysis to investigate gene expression and DNA methylation patterns associated with hypertrophic cardiomyopathy (HCM). The researchers found significant downregulation of mitochondrial and energy-related pathways, highlighting mitochondrial dysfunction—particularly altered PINK1 expression—as a potential contributor and therapeutic target in HCM.

Read More...